If Your Lip Gloss Isn’t Peptide-Infused, You’re Missing Out! Check out these 5 brands

The beauty industry is continuously evolving, with new trends emerging every year. In 2025, peptides, known for their skin-enhancing properties, are poised to take center stage in lip gloss formulations. These tiny protein fragments are instrumental in supporting collagen synthesis, which translates to fuller, more hydrated lips. 

1) Iris&Romeo Power Peptide Lip Balm- $26

(CLECO Clean Score: 9.5/10)

Main Ingredients: Biomimetic Triple-Peptides, Rose Wax Complex (Rosa Damascena, Rosa Centifolia), Shea Butter, Rose Hip Oil, Camellia Oil.  

  1. Why this score: Adheres to very strict "clean" standards (EU+), features clinical levels of peptides, nourishing natural oils/butters, cruelty-free, recyclable packaging.  

  2. How it could improve: Explicitly naming the specific peptides used would enhance transparency.

  3. Potential Risks: Very low risk. Minor potential for sensitivity to complex botanicals in highly reactive individuals.

2) Farmacy Beauty Apple Peptide Lip Smoothie- $22.00

CLECO Clean Score: 8.5/10

Main Ingredients: Palmitoyl Tripeptide-1, Vitamin C (Tetrahexyldecyl Ascorbate), Upcycled Apple Extract, Shea Butter, Mango Seed Butter. (Base includes Hydrogenated Polyisobutene, Diisostearyl Malate).

  • Why this score: Contains peptides, Vitamin C, beneficial butters, strong clean standards (Leaping Bunny certified), sustainable aspects (upcycled ingredients, recyclable packaging), natural flavor.

  • How it could improve: Uses some common synthetic emollients/waxes and lake colorants, which some ultra-strict clean users might avoid.

  • Potential Risks: Low risk. Contains Limonene (in natural flavor) - potential allergen. Synthetic base ingredients generally safe but noted for strict natural adherents.

3) Biossance Squalane + Pro-Peptide™ Lip Perfector- $18.00

CLECO Clean Score: 8.5/10

Main Ingredients: Pro-Peptide™ Complex, Squalane, Micro-Encapsulated Hyaluronic Acid.

  • Why this score: Features a specific peptide complex, signature clean Squalane, and HA. Prioritizes clean, sustainable, effective formulations.

  • How it could improve: Some users report taste/texture inconsistencies. Full transparency on natural flavor components is ideal.

  • Potential Risks: Low risk. Potential sensitivity to natural flavorings. Texture issues affect experience, not safety.

4) Kosas Wet Lip Oil Gloss- $24

CLECO Clean Score: 8.5/10

Potential Risks: Low risk. Small chance of sensitivity for highly reactive individuals due to multiple botanicals.

5) Rhode Peptide Lip Treatment (Unscented) - $18

CLECO Clean Score: 8/10

Main Ingredients: Contains peptides and effective, simple moisturizers (Shea Butter, Babassu, Cupuaçu).

  • Why this score: The unscented version directly addresses concerns about fragrance allergens/irritants. Cruelty-free and vegan. Relatively straightforward, hydration-focused formula.

  • How it could improve: Some users have reported issues with the formula becoming gritty over time, suggesting potential stability or crystallization issues with certain ingredients (like Shea Butter) under varying temperatures, though this doesn't necessarily mean it's unsafe. Greater transparency on peptide sourcing/concentration could be beneficial.

  • Potential Risks: Low risk, especially the unscented version. The main reported issue is the potential for texture changes (grittiness), which affects usability but isn't a health hazard.

Cléco Official

Clèco Official is your go-to for conscious living & info—spotlighting innovators, fashion, beauty, wellness, and health news that matter. All product picks are independently chosen; we do not earn from links or purchases.

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